Sarcoma Care

Our best-in-class cancer specialists use the most advanced techniques to treat all kinds of sarcomas.

Sarcoma Care

Our best-in-class cancer specialists use the most advanced techniques to treat all kinds of sarcomas.

USC Norris Comprehensive Cancer Center

Our oncology experts work together as a team to deliver patient-centered cancer care.

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USC Orthopaedic Surgery

Our nationally recognized doctors treat a wide range of conditions, including benign and malignant tumors.

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Donations

Support our efforts to advance and innovate sarcoma care.

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Cutting-Edge Care for All Types of Sarcomas

Sarcoma is a type of cancer that affects the bones and soft tissues of the body. Our USC Sarcoma Program specialists deliver expert care and advanced treatments for all types of sarcomas. We are ranked among the top cancer programs in the nation, according to U.S. News & World Report.

Our best-in-class specialists coordinate your care from diagnosis to treatment to recovery. Our sarcoma experts work closely with specialists in surgery, orthopedic surgery, radiation and medical oncology, pathology and musculoskeletal radiology to deliver integrated care. We are helping pioneer innovative sarcoma treatments through our collaboration with the National Cancer Institute (NCI) cooperative groups and pharmaceutical partners. As an NCI-designated Comprehensive Cancer Center, we offer a level of expertise found only in the top cancer centers across the country.

Sarcoma Treatment Tailored Just for You

We focus on understanding your condition and designing a treatment plan tailored to your unique sarcoma type and stage. Our team offers access to a combination of effective treatment options, including surgery, radiation therapy, immunotherapy, chemotherapy, targeted therapies and clinical trials evaluating novel therapeutics. If surgery is required, we specialize in advanced techniques to remove tumors and preserve your limbs. We offer a wide range of advanced treatment therapies for sarcoma, including intensity modulated radiation therapy (IMRT), cryoablation and bloodless surgical options.

We focus on unique, minimally invasive surgical interventions to not only ablate a lesion but also to support and reconstruct bone defects using your own bone. We are also able to use unique prosthetic devices to reconstruct not only large segments of bone but large segments of bone and joints together, as well as soft tissue reconstructions using allograft soft tissues.

Why Choose Us for Sarcoma Care

  • Our doctors have decades of experience in sarcoma treatment.
  • We have the most experienced multidisciplinary sarcoma team in Southern California.

Multiple studies have documented that patient outcomes are better at sarcoma centers with multidisciplinary teams and high patient volumes like we have at Keck Medicine of USC.

Conditions We Treat

  • All types of sarcomas
  • Chondrosarcoma
  • Ewing’s sarcoma
  • Osteosarcoma
  • Soft tissue sarcoma
  • Gastrointestinal stromal tumor (GIST)
  • Leiomyosarcoma
  • Liposarcoma
  • Malignant peripheral nerve sheath tumor
  • Rhabdomyosarcoma
  • Synovial sarcoma

Treatments We Offer

  • Chemotherapy
  • Cryoablation
  • Intensity modulated radiation therapy (IMRT)
  • Radiation therapy
  • Surgery, including bloodless surgical options
  • Targeted therapy

USC Norris Comprehensive Cancer Center

Our oncology experts work together as a team to deliver patient-centered cancer care.

Learn more

USC Orthopaedic Surgery

Our nationally recognized doctors treat a wide range of conditions, including benign and malignant tumors.

Learn more

Donations

Support our efforts to advance and innovate sarcoma care.

Make a gift

Surgical Care

Routinely performing complex surgeries on tumors throughout the body, including the limbs, trunk and back of the abdomen.

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Clinical Trials

Giving patients access to new and promising sarcoma therapies.

Find an open trial
A man, doctor Ramzi Ben Youssef, helps a female patient receiving physical therapy at an inpatient rehab center

Rehabilitation Care

Helping you regain independence and mobility so you can get back home.

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Radiation Therapy

Leveraging advanced radiation oncology technologies, including stereotactic radiosurgery, brachytherapy and image-guided radiation therapy.

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A female Keck Medicine oncology expert in a mask and face shield examines a female lung cancer patient with a stethoscope

Survivorship

Helping patients rebuild strength, manage symptoms and lead healthy lives after cancer treatment.

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World-Class Leadership

Our internationally renowned physicians and clinicians are leaders in cutting-edge treatments, breakthrough research, and exceptional outcomes.

Mark Agulnik, MD

Section Chief of Sarcomas & Melanoma, Professor of Medicine

J. Dominic Femino, MD

Chief of Musculoskeletal Oncology

Mark Agulnik, MD

Accepting new patients
Specialties
Medical Oncology, Sarcoma
Specialties
Pathology, Gastrointestinal Pathology, Liver Pathology  View more

J. Dominic Femino, MD

Accepting new patients
Associate Professor of Clinical Orthopaedic Surgery
Specialties
Orthopedic Oncology, Orthopedic Surgery, Sarcoma

James S. Hu, MD

Accepting new patients
Professor of Medicine
Specialties
Medical Oncology, Sarcoma

H. Paco Kang, MD

Accepting new patients
Assistant Professor of Clinical Orthopaedic Surgery
Specialties
Orthopedic Oncology, Orthopaedic Surgery, Sarcoma
Specialties
Radiation Oncology, Sarcoma

Lee Michael Zuckerman, MD

Accepting new patients
Associate Professor of Clinical Orthopaedic Surgery
Specialties
Orthopedic Surgery, Orthopedic Oncology, Sarcoma
Specialties
Sarcoma
Specialties
Nurse Practitioner, Sarcoma

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