Rose Lai

Associate Professor Director of Translational Neuro-oncology

Areas of treatment:

Primary brain tumors
Malignant glioma
Glioblastoma multiforme
Metastatic cancers/tumors to the brain and spine
Leptomeningeal diseases/leptomeningitis/neoplastic meningitis
Neurological complication of cancers


  • Neurology
  • Oncology


  • Department of Medicine
  • Department of Neurological Surgery
  • Department of Neurology


  • Cantonese
  • English
  • French

Rose Lai, MD, MS

Associate Professor
Director of Translational Neuro-oncology

Practicing location:

  • USC Norris Comprehensive Cancer Center and Hospital

About this doctor:

Dr. Lai’s goal as director of Translational Neuro-Oncology at USC is to advance the USC Brain Tumor Center at USC Norris Cancer Hospital as the premier clinical and research program in neuro-oncology, both nationally and internationally. Dr. Lai comes to USC with more than 10 years of experience in the treatment of nervous system cancers. She previously had an established clinical practice at the Brain Tumor Center of NewYork-Presbyterian Hospital/Columbia University Medical Center. With extensive expertise in the management of primary brain tumors, metastatic diseases and neurological complication of cancers. Her key research goal is to develop clinical trials for brain tumor patients based on promising therapeutics from the laboratory. She is actively planning trials in brain tumor vaccines, novel small molecules compounds and innovative drug delivery techniques. As the director of Translational Neuro-Oncology at USC, she brings in strong experience in leading successful national and international trials. She has also served on the steering committee and planning committee of brain tumor trials staged by major biotechnology companies. Dr. Lai is actively investigating the genetic risk factors of brain tumors. She has built a program with funding from the National Cancer Institute (NCI) that evaluates the interactions of environmental and genetic risk factors in the causation of glioma, a common type of primary brain tumor. She has also served as principal investigator and steering committee member in the Gliogene Consortium, which is an international group of eminent scientists whose goal is to unravel the genetic cause of glioma. The consortium’s work is also funded by the NCI. Dr. Lai is a sought-after peer reviewer of grants submitted to the National Cancer Institute’s population sciences study section and institutional translational grant award at Columbia University.


Doctor of Medicine, University of Western Ontario, London, ON
Master in epidemiology from McMaster University, Hamilton, ON


Internship in internal medicine, Cleveland Clinic, Ohio


Residency in neurology, the Neurological Institute of Columbia University, N.Y.


Fellowship in neuro-oncology, Memorial Sloan Kettering Cancer Center, N.Y.
Fellowship, Neuro-oncology (in Medical Oncology)
Juravinski Cancer Center, McMaster University, Hamilton, Ontario

Professional society memberships:

98 - present American Academy of Neurology
00 - present Society of Neuro-oncology
01 - present American Society of Clinical Oncology
02 - present American Association of Cancer Research
06 - present Brain Tumor Epidemiology Consortium
09 - present American Society of Preventive Oncology


Society for Neuro-Oncology's Excellence in Epidemiology Award, 2010
Ontario Graduate Scholarship, 2004
Chief fellow of neuro-oncology at Memorial Sloan Kettering Cancer Center, 2001-2002