Lawrence R. Menendez

Chief, Center for Musculoskeletal Oncology Professor of Clinical Orthopaedic Surgery

Areas of treatment:

Tumors of the musculoskeletal system in adults and children
Limb sparing tumor surgery
Innovative methods of endoprosthetic and allograft reconstruction
Cryosurgery for bone and soft tissue tumors
Tumors of the extremity, shoulder girdle, pelvis and sacrum
Soft tissue sarcomas
Metastatic carcinomas
Melanomas of the extremities
Musculoskeletal infections
Periprosthetic joint infections


  • Orthopaedic Surgery


  • Department of Orthopaedic Surgery


  • English
  • French
  • Portuguese
  • Spanish

Lawrence R. Menendez, MD, FACS

Chief, Center for Musculoskeletal Oncology
Professor of Clinical Orthopaedic Surgery

Practicing locations:

  • Keck Hospital of USC
  • USC Healthcare Center 2
  • USC Norris Comprehensive Cancer Center and Hospital

About this doctor:

Dr. Lawrence R Menendez is a full-time, senior member of the Department of Orthopaedic Surgery at the Keck Medical Center of USC where he specializes in the management of malignant and benign tumors of bone and soft tissue. He is one of only a handful of orthopaedic oncologists in Southern California who is experienced in performing complicated limb-sparing surgeries and other orthopaedic cancer techniques such as cryosurgery and radiofrequency ablation. Primary musculoskeletal cancers are rare. Dr. Menendez has treated these tumors regularly since 1985 and thus he is highly experienced and qualified to manage patients with these problems. Dr. Menendez uses a coordinated, multidisciplinary approach to treatment with his colleagues from medical oncology, radiation oncology, nuclear medicine, radiology, surgical pathology, occupational and physical therapy and social services and pain management. Over the years, he has developed a special interest in the treatment of tumors of the pelvis and sacrum. Dr. Menendez joined the faculty at USC in 1985 after his fellowship. Dr. Menendez has been involved in clinical research for over 27 years and is the author of numerous peer-reviewed research articles, book chapters and presentations. He has been invited to speak at universities both in the United States and abroad. Dr. Menendez received his medical degree from New York University School of Medicine where he was elected to the Alpha Omega Honor Society. He completed a fellowship in orthopaedic oncology at the prestigious University of Florida oncology program under the guidance of Dr. William F. Enneking.


Medical Degree - New York University School of Medicine, 1979


Columbia Presbyterian Medical Center 1979-1980


New York University Medical Center, Orthopaedic Surgery, 1980-1984


University of Florida Academic Health Center, Musculoskeletal Oncology and Pathology, 1984-1985


American Board of Orthopaedic Surgery, 1987

Professional society memberships:

Fellow, American Academy of Orthopaedic Surgeons
Fellow, American College of Surgeons
Member, Musculoskeletal Tumor Society
Member, Society of Surgical Oncology
Member, International Society of Limb Salvage
Member, Western Orthopaedic Association
Member, American Medical Association
Alpha Omega Alpha Honor Society


Castle Connolly "Top Doctor,” 2015
Best Orthopaedic Surgeons by The Hollywood Reporter in 2014
Super Doctor by Los Angeles Magazine in 2014